Companies

Cassidy Bio

cassidybio.com

Cassidy Bio develops AI-powered genomic foundation models for safer, scalable therapeutic gene-editing design.

HQTel Aviv, null, Israel
Employees11-50
Funding$8M
Profile 3mo agoJobs checked 3d ago
Specialization
Biotechnology
Business
Model Development
Market
Life Sciences
Ecosystem
AI for science
Customers
Enterprises
More details
Organization type
Commercial Company
Ecosystem
AI for science
Business
Model Development
Specialization
Biotechnology
Market
Life Sciences
Customers
Enterprises
Delivery models
Not classified
Revenue models
Not classified
Listing status
Not classified
Latest equity round
Seed
Reported funding amount
$1M-$10M

About

Cassidy Bio builds an AI-driven genomic foundation model and programmable platform for designing therapeutic gene-editing systems. It targets therapeutic gene-editing partners, differentiating through proprietary wet-lab data, population-scale genomics, and closed-loop prediction and validation that ranks designs for safety and efficacy.

Market

Cassidy Bio competes in AI-enabled computational design software for therapeutic genome editing and genetic medicines, positioning itself as an intelligence layer and programmable, end-to-end design platform rather than a single guide-design utility. Its differentiation is the combination of proprietary therapeutic-condition wet-lab and NGS data, a model trained on 70,000 genetically diverse genomes with population-aware safety, and closed-loop predictions spanning guides, editors, delivery context, efficacy, safety, and repair outcomes; this is broader than narrower guide-design tools such as Benchling and editor-design platforms such as Profluent.

Target Customers

Primary customers are biotech and pharmaceutical R&D organizations developing therapeutic gene-editing medicines, especially teams responsible for gRNA and editor selection, genomic-variation assessment, cell-type matching, and multiplex-edit planning. The likely buyers are genome-editing, computational-biology, or translational-development leaders seeking to reduce experimental design cycles; the evidence points to partner organizations rather than consumers or general-purpose research users.

At a Glance

Problem

Genome-editing medicines are difficult to design reliably because teams must navigate guide-RNA selection, editor choice, patient-specific genomic variation, repair outcomes, safety, and delivery context. Cassidy frames the central pain as a process built on multi-year, multi-team trial-and-error: the apparent speed of the bespoke CRISPR therapy that saved Baby KJ in early 2025 depended on extensive prior experimentation and international collaboration. The economic burden is therefore the time and resources required to identify viable therapeutic candidates, as well as the cost of delaying potentially life-saving treatments.

The killer use case is making bespoke or otherwise highly tailored genome-editing therapies reproducible rather than one-off successes. Cassidy aims to give therapeutic developers clinical confidence at the earliest design stage, helping them choose patient-fit guides and editors and move from years of experimentation toward weeks or days of predictive selection.

Product / Service

Cassidy offers a partner-facing computational platform positioned as an “intelligence layer for gene editing.” Its specialized genomic foundation model is designed to engineer complete genome-editing systems, spanning guide design, enzyme selection, genomic variation, and delivery contexts. The company says its platform shortlists candidates across these dimensions and enables partners to move faster and smarter in therapeutic gene editing; its website also promotes an online guide-design prediction tool.

The model is built through a closed loop of biology and computation. Cassidy generates proprietary wet-lab data using high-throughput assays and NGS validation, trains the model on 70,000 genetically diverse human genomes, predicts efficacy, safety, repair outcomes, and genomic diversity in silico, and feeds experimental results back into the system. The intended benefit is to reduce trial-and-error from years to days or weeks while embedding population-aware safety and contextual knowledge into the design process.

Market

Cassidy competes in the emerging market for AI-enabled computational genomics and genome-editing design software, serving biotechnology and therapeutic-development partners rather than selling an approved therapy itself. The company’s positioning is differentiated around an end-to-end genomic foundation model for therapeutic editing. The supplied company material does not identify specific direct competitors, so Cassidy’s precise competitive set cannot be established from the available evidence.

Cassidy says it was founded in 2024, and its site presents a live prediction-tool demo and states that it is backed by investors. These are signs of an early-stage platform seeking adoption, but the available material does not disclose revenue, paying customers, partnerships, financing amounts, or clinical programs. It is therefore best characterized as pre-revenue or revenue-undisclosed and early commercial, rather than as a company with demonstrated market traction. Its opportunity is supported by a still-nascent therapeutic category: the site describes CASGEVY as the only genome-editing therapy on the market at the time of its cited timeline, underscoring the large gap between research breakthroughs and scalable approved medicines.

Founders & Leadership

Rom KshukFounder
Co-Founder & CEO
Ayal HendelFounder
Co-Founder & CSO
Yaniv ShmueliFounder
Co-Founder & CTO

Funding History

2025-11
Seed$8M

Ahren Innovation Capital

Recent News

2025-11-24funding
Model ML raises again, gene-editing gains backers and Solventum's wound care buy

Axios reported that Israeli gene-editing company Cassidy Bio raised an $8 million seed round. Ahren Innovation Capital led the round, with participation from Lool Ventures and 10D VC.

2025-11-20product_launch
Cassidy Bio Launches with the Goal to Develop Safer, More Scalable Gene Editing Therapies

CRISPR Medicine News published Cassidy Bio’s launch announcement, including details of its $8 million seed financing led by Ahren Innovation Capital. The company said the funding would advance an AI-first platform continuously trained and validated through wet-lab experimentation.

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Business Model

Cassidy Bio appears to use a B2B partnership model, providing therapeutic gene-editing developers access to its predictive design platform and genomic intelligence. Public materials do not disclose specific subscription, licensing, usage-based, or milestone pricing.

Products

AI-powered genomic foundation model for therapeutic genome-editing designGuide-design prediction toolTherapeutic design applications for patient-fit guide and editor selection, genomic-variation analysis, cell-type matching, and multiplex-edit repair-outcome planning

Tech Stack

AI and machine learningGenomic foundation modelPopulation-scale genomics using 70,000 genetically diverse human genomesProprietary therapeutic-condition wet-lab datasets and high-throughput assaysNext-generation sequencing (NGS) validationIn silico predictive modeling for efficacy, safety, repair outcomes, and genomic diversityClosed-loop experimental validation

Competitors

Benchling
Form Bio
Profluent
Biomod AI

Key Investors

Ahren Innovation Capital, Lool Ventures, 10D VC, AstraZeneca, Merck KGaA