About
Craniometrix provides full-service, non-clinical care navigation for dementia patients and their families through healthcare clinics. Its human navigators are supported by AI that handles documentation, care-plan preparation, follow-up tracking, and research, while the service is built on Johns Hopkins’ MIND at Home program and covered through Medicare’s GUIDE Model.
Market
Craniometrix competes in dementia-care navigation and digital health, with a specific focus on helping medical practices implement Medicare’s GUIDE Model. Its positioning is an outsourced, non-clinical support layer that combines the evidence-based MIND at Home program and real human navigators with AI-enabled operational assistance. The main differentiation is that AI handles documentation, preparation, pattern-spotting, and coordination while humans retain every patient and family conversation, allowing clinics to launch the service without adding staff or changing workflows.
U.S. neurology and primary-care clinics and medical practices serving dementia patients, particularly providers implementing Medicare’s GUIDE Model. The primary buyer is the practice or provider organization seeking to add non-clinical dementia navigation without hiring staff or rebuilding workflows; families are the supported end users.
At a Glance
Problem
Dementia care is a high-touch, long-duration coordination problem that families are typically left to manage alone. Craniometrix says 11 million Americans care for someone with dementia, mostly unpaid and without a roadmap; after diagnosis, families often receive little more than information and must navigate behavioral changes, benefits, respite, specialists, hospital transitions, and day-to-day decisions themselves. The resulting burden is both emotional and economic: inadequate non-clinical support can contribute to avoidable crises and hospitalizations, while clinicians lack the staff and time to provide continuous help between visits.
The company’s central use case is keeping a person with dementia safely at home while helping the family manage the disease. Craniometrix cites evidence that the underlying care model can avoid roughly 30% of hospitalizations, and Medicare’s GUIDE Model now reimburses this type of support. That creates a three-sided economic proposition: families receive the service at no cost, practices avoid building a new care-navigation team, and providers can generate new GUIDE-related revenue while reducing workload.
Product / Service
Craniometrix is a full-service dementia care-navigation layer for neurology and primary-care practices. It combines the Johns Hopkins-originated MIND at Home program with real human coaches who provide personalized care plans, caregiver coaching, community-resource referrals, respite coordination, care coordination, and a 24/7 support line. The service is delivered alongside the clinic rather than replacing it: the physician retains clinical ownership while Craniometrix supplies the non-clinical navigation and family support required by GUIDE.
Its software, including the AI assistant Alfred, handles documentation, call summaries, patient-history review, care-plan preparation, pattern spotting, follow-up tracking, resource research, and suggested next actions. AI is used to remove administrative work and help navigators manage larger caseloads, but it does not speak directly with patients or families; those interactions remain with a human navigator. For providers, Craniometrix handles enrollment, staffing, and technology end to end, promising implementation in weeks without new hires or a workflow rebuild.
Market
Craniometrix competes in dementia care navigation, caregiver support, chronic-care management, and GUIDE Model enablement within digital health. Its differentiation is the combination of a reimbursable Medicare pathway, a human-delivered service, an evidence-based Johns Hopkins care model, and software intended to make that service scalable for clinics. It is therefore closer to navigation infrastructure and outsourced care operations than to a standalone cognitive-assessment app or consumer chatbot.
The competitive field includes both dementia-support technology companies and larger organizations that provide senior or dementia care. Tracxn identifies RecallCue, Memory Lane Games, and Silvia as competitors or alternatives, while Crunchbase lists Home Instead, CenterWell Senior Primary Care, and CareMore Health as possible adjacent competitors. Craniometrix is not pre-revenue: its Y Combinator profile says it launched the care-navigation service in July 2025, reached $8 million in ARR, and raised a $15 million Series A; its website says it is live in more than 50 clinics and partnered with more than 1,000 physicians. The company also says it has raised more than $21 million overall and is backed by Y Combinator, although these traction and funding figures are company-reported rather than independently audited.
Founders & Leadership
Funding History
Quiet Capital, Defy.vc, Olive Tree Capital, Rebel Fund, J Ventures, Cathexis Ventures, Y Combinator
J Ventures, Defy Partners Management, Y Combinator
Recent News
Y Combinator’s 2026 health-tech directory reports that Craniometrix has raised more than $21 million and recently completed a $15 million Series A. The profile positions the company as scaling AI-enabled dementia care navigation.
Craniometrix highlights its partnership with MIND at Home, the Johns Hopkins Medicine-created dementia-care model, which it delivers through its GUIDE platform. The company also says Craniometrix and Johns Hopkins are collaborating on a study.
The startup-focused publication reported that Craniometrix had raised a $15 million Series A in early 2026 and reached $4 million in ARR. It described the company’s AI-supported dementia care-navigation platform and Medicare-covered coaching model.
Arizona Neurology Associates announced a new Medicare-funded GUIDE service with Craniometrix for qualifying dementia patients and caregivers. Arizona Neurology Associates continues medical care while Craniometrix provides caregiver support, care navigation, and social-needs assistance.
CNMRI 2.0 announced a partnership with Craniometrix to provide free dementia-support services for qualifying patients through the GUIDE Program. Listed services include caregiver education, care coordination, community resources, 24/7 support, and Medicare-funded respite care.
Coastal Neurology said it was partnering with Craniometrix and the Johns Hopkins-managed MIND at Home program through GUIDE. The partnership is intended to support patients and families receiving dementia care.
Active Roles
12Business Model
Craniometrix provides GUIDE-covered dementia coaching and care-navigation services through provider practices, with no direct cost to patients or practices. Its revenue model is tied to Medicare’s GUIDE reimbursement for eligible enrolled patients; CMS says participants can receive up to $2,500 annually per eligible patient.