Companies

Prescience, Inc.

getprescience.com

AI-native employer health-benefits platform combining physician-led plans, predictive care, and transparent pricing.

HQBoston, Massachusetts, United States
Employees1-50
3 active roles
Jobs checked 17h ago
Healthcare AIAI Application

About

Prescience, Inc. is building an AI-native health-benefits platform and new healthcare system for employers, particularly startups and ambitious companies. It combines employer health plans with physician-led plan design, predictive care navigation, direct provider relationships, and transparent pricing to reduce costs while improving benefits. Its differentiation is proactive, data-driven intervention rather than relying on denials, middlemen, or conventional fully insured plans.

Market

Prescience competes in employer-sponsored health benefits and health-tech/insurtech, with a particular focus on startups and modern employers that may otherwise use a PEO or conventional fully insured plan. It positions itself as a physician-led, integrated alternative that combines plan administration, care navigation, HSA funding, and premium employee benefits. Its main differentiation is the use of AI-driven predictive care routing and a 24/7 AI care companion alongside human physicians, rather than offering only benefits administration or insurance distribution.

Target Customers

Prescience targets startup employers with 10+ employees and other ambitious, modern companies seeking an alternative to PEO or fully insured health plans. The primary buyer is the employer or plan sponsor—typically a founder, operations leader, or benefits/people leader—looking for lower costs, premium benefits, and reduced administrative overhead.

At a Glance

Problem

Prescience addresses the employer health-benefits problem: healthcare is expensive, administratively opaque, and often delivers poor outcomes for both companies and employees. Its materials cite employer health costs of $530 billion and 1.4 billion lost workdays annually, while its About page points to 2025 annual family premiums approaching $27,000. For employees, the pain shows up as confusing plan documents, deductibles, surprise bills, denials, long waits, and having to navigate outdated call centers.

The central use case is an employer trying to control health spend without offering worse benefits. Prescience aims to identify health risks early and route employees to lower-cost, higher-quality care before problems become expensive events. Its illustrative example compares a predicted $26,600 ER visit and MSK surgery pathway with an AI-routed path costing $890, while its YC profile claims potential employer savings of 20–50%.

Product / Service

Prescience is a managed employer health-benefits platform combining plan design, administration, care navigation, insurance-related services, and employee financial tools. Its MD-led team designs a tailored plan, promises implementation in days rather than months, and operates the back office: employers connect payroll while Prescience handles filings, claims, COBRA, and real-time claims administration. The company positions this as a direct alternative to broker-heavy and middleman-dependent benefits administration.

For employees, the product is a member-facing health plan and care experience built around a 24/7 AI Care Companion. The system can use wearable and medical-record data to triage needs, involve Prescience physicians, and route members to appropriate in-network care quickly, with transparent prices and same-day availability where possible. The offering also includes features such as just-in-time HSA funding, premium benefits including GLP-1 coverage and wearables, and a simpler enrollment and benefits experience. The intended benefit is to reduce employer cost while improving access, predictability, and perceived richness of coverage.

Market

Prescience competes in employer health benefits and health-plan administration, with overlap across insurtech, alternative-funded health plans, care navigation, and benefits fintech. Its own savings calculator frames the competitive set as PEOs such as Rippling, Justworks, Gusto, and TriNet; fully insured plans from Blue Cross, United, Aetna, and Cigna; and ICHRA providers or options including Thatch, Take Command, and Oscar. Prescience differentiates itself through an integrated plan, administrative service, AI-driven care routing, and an explicit cost-savings proposition rather than through benefits software alone.

The company appears to be at an early commercial stage. Y Combinator lists Prescience, Inc. as founded in 2026, part of the Summer 2026 batch, active, based in Boston, and consisting of a two-person team. Prescience's member materials refer to design partners running its Diamond plan today, but the reviewed sources do not disclose named customers, enrollment, revenue, or a larger operating scale. Accordingly, the strongest public traction signals are YC acceptance, an active product and employer sales process, and design-partner activity; the available evidence does not establish whether the company is revenue-generating or pre-revenue.

Founders & Leadership

Rishab JainFounder
Chief Executive Officer
Aditya Jain, MDFounder
Chief Operating Officer

Recent News

2026-07-21
Prescience, Inc.: Healthcare for the age of abundant intelligence.

Y Combinator announced Prescience as a Summer 2026 company building an AI-native health insurance and employer health-benefits platform. The company says it can save employers 20–50% on healthcare while providing modern benefits.

2026-05-15product
Member Health Benefits Experience

Prescience introduced its member-facing benefits experience, including a 24/7 care companion, health-data integration, and benefits such as free Whoop devices and GLP-1 coverage.

2026-04-26
Manifesto — Prescience, Inc.

Prescience published its vision for rebuilding the U.S. healthcare system around AI, proactive care, redesigned risk pricing, and earlier disease anticipation.

Active Roles

3
San Francisco, CA, US/Engineering/3d ago
San Francisco, CA, US/Operations/3d ago
San Francisco, CA, US/Engineering/5d ago

Business Model

Prescience sells employer-sponsored health-benefits plans and related administrative, care-navigation, and health-plan services. Employers fund the plans, while Prescience positions its transparent pricing and direct provider contracting as alternatives to PEO and fully insured arrangements; the exact fee schedule or per-member pricing is not publicly disclosed.

Products

Employer health-benefits platform with physician-led custom plans, including the Diamond plan24/7 Prescience AI Care Companion with escalation to Prescience physiciansCare-navigation app with transparent provider pricing, wait times, and appointment availabilityJust-in-time HSA wallet and funding system with a curated health and wellness marketplacePrescience Time Machine predictive care-routing system for proactive, lower-cost care

Tech Stack

AI and machine-learning systemsFoundation model for predictive care routingAlphaGo-like Time Machine trajectory-optimization systemWearable and medical-record data integration24/7 AI care companion with physician escalationFintech/HSA wallet and just-in-time funding infrastructure

Competitors

Thatch
Sana Benefits
Gravie
Collective Health
Rippling