About
Living Models builds foundation models for biology, beginning with BOTANIC, an open-weight genomic transformer trained across plant species to improve trait prediction and crop-breeding efficiency. It sells primarily to seed companies, breeders, and research institutions, differentiating through cross-plant genomic learning and secure customer fine-tuning that keeps proprietary data within customers’ environments.
Market
Living Models competes in AI-for-biology, plant genomics, and agricultural crop-breeding software, positioning itself as an intelligence and foundation-model layer for accelerating crop-trait discovery and breeding. Its differentiation is a plant-first approach using open-weight, DNA-focused models trained on large plant-genome collections, while competitors range from broader biological foundation models such as Arc Institute’s Evo 2 and InstaDeep’s Nucleotide Transformer to integrated crop-breeding and gene-editing companies such as Inari and Pairwise.
Living Models primarily targets B2B agricultural organizations: global seed companies, regional breeding programs, and underserved crop initiatives. The likely buyers are plant-breeding, genomics, computational-biology, and R&D teams seeking to predict gene function, regulatory elements, trait associations, and candidate varieties.
At a Glance
Problem
Living Models is tackling the slow, expensive crop-discovery pipeline. Developing a single crop trait can take more than eight years, while the roughly $60 billion crop-protection market still relies heavily on workflows developed before modern genomics. Climate volatility increases the cost of this delay: seed and breeding companies need to identify useful traits faster, but conventional genomic-selection models are often narrow, crop-specific, and data-hungry.
The principal use case is accelerating crop breeding. BOTANIC is designed to scan a plant genome, rank candidate genes or genomic regions by their predicted phenotypic impact, and direct breeders toward the small number of candidates worth validating physically. In principle, this turns a largely empirical, multi-year search for improved yield stability or other traits into a weeks-long computational prioritization exercise.
Product / Service
Living Models is building foundation models for biology, beginning with BOTANIC, a family of genomic transformer models for plant biology. BOTANIC-0 learns patterns in DNA and can predict gene function, regulatory elements, and trait associations. The company says the model was trained across 43 plant species and more than 60 billion base pairs, with up to one billion parameters, and has matched leading academic genomic models on 22 benchmark tasks while using comparatively modest initial compute.
The commercial model is intended to combine open research with enterprise licensing. Seed companies and research institutions can fine-tune BOTANIC inside secure environments using their own data, while retaining ownership and control of that data; Living Models says it will co-develop integrations that fit existing R&D workflows. The company claims this approach can reduce the crop-development cycle from eight-plus years to roughly two or three by concentrating physical experiments on the most promising candidates.
Market
Living Models competes in biological foundation models, computational genomics, and AI-enabled agricultural research, with an initial focus on plant genomics and crop breeding. Its disclosed technical comparators include leading academic genomic work associated with Cornell and InstaDeep, while the broader category includes companies developing foundation models for DNA, RNA, proteins, and multi-omics data. Living Models is differentiated by specializing its initial model family in plants and by emphasizing deployment against customers’ private breeding data rather than requiring that data to leave their environment.
The company appears to be at an early commercialization stage rather than a mature revenue business. It emerged from stealth in March 2026 with a $7 million seed round, has made BOTANIC open weights and research available, and secured funding for a dedicated 120-GPU NVIDIA B200 cluster. It reports initial commercial traction in North America and Europe and academic partnerships with INRAE, Paris-Saclay Plant Science Institute, CRAG Barcelona, Aarhus University, and the University of Florida, but no revenue or customer-count figures are disclosed in the available research.
Founders & Leadership
Funding History
Asterion Ventures, The Galion Project
Recent News
Diginomica reported that Living Models launched BOTANIC, a family of transformer models trained on plant genomic sequences, and is training an open-weight model.
TechRadar profiled Living Models' approach to DNA-trained AI foundation models and their potential applications in plant biology.
AgNavigator reported that Living Models emerged from stealth with $7 million in seed funding to develop plant-genomics foundation models intended to improve crop breeding and trait prediction.
TamRadar reported that Living Models raised a $7 million seed round for AI foundation models in plant biology, starting with open-source BOTANIC trained on more than 1,600 genomes.
Tech.eu reported that the Paris–Berkeley startup raised $7 million in seed funding as it emerged from stealth to develop foundation models for biology trained on DNA rather than text or code.
GenomeWeb reported that Living Models planned to use its seed funding to expand computing resources and build a larger version of BOTANIC, its foundation model for plant biology.
A bioRxiv preprint introduced Botanic0, a family of plant-genomic foundation models ranging from 100 million to 1 billion parameters and pretrained on 43 diverse plant species. Living Models identifies BOTANIC as its first family of foundation models for plant biology.
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Get notified when they postBusiness Model
Living Models plans to commercialize BOTANIC through licensing to seed companies and research institutions, enabling customers to fine-tune the model in secure environments. It also co-develops integrations with customers; specific pricing has not been publicly disclosed.
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Key Investors
Asterion Ventures, The Galion Project, Kima Ventures, STATION F, UC Berkeley SkyDeck, Juniper Square, Pascual Innoventures, Artesian