Companies

Mango Medical

mangomedical.io

Mango Medical turns orthopedic imaging into patient-specific surgical plans for faster, more precise procedures.

HQSan Francisco, California, United States
Employees1-50
Jobs checked 5m ago
Healthcare AIAI ApplicationB2B SaaSPre-Seed / Seed

About

Mango Medical builds agentic AI that converts CT scans and X-rays into patient-specific orthopedic surgical plans. Its primary customers are orthopedic implant companies and surgeons, while its key differentiation is delivering surgeon-ready plans in seconds or minutes rather than the multiple days traditionally required.

Market

Mango Medical competes in AI-enabled orthopedic preoperative and surgical-planning software, serving both arthroplasty and trauma/fracture workflows. Its positioning is API-first and agentic: it converts CT/X-ray data into patient-specific plans in seconds or minutes rather than the conventional multi-day planning cycle, differentiating it from established templating tools and narrower procedure-specific platforms; the company is still pursuing FDA 510(k) clearance.

Target Customers

Mango Medical primarily targets orthopedic implant manufacturers and orthopedic surgeons, including trauma and arthroplasty teams that need patient-specific surgical plans. Its initial enterprise workflow is API-based: implant companies submit patient CT scans and receive implant-sizing, surgical-approach, and broader planning outputs rapidly, with shoulder replacement identified as the starting procedure.

At a Glance

Problem

Orthopedic surgery still has a costly preoperative-planning bottleneck. Joint-replacement plans can take two to five business days, while acute and complex fractures often lack comparable planning workflows, forcing surgeons to determine treatment during the operation. That can create trial and error, wasted operating-room time, wrong implant selection, complications, and revision surgeries. The broader economic burden is substantial: fractures are associated with an estimated annual cost of €37.5 billion in Europe.

Mango Medical’s clearest use case is patient-specific planning for complex, time-sensitive acute fractures, a category the company estimates at roughly 15 million surgeries annually. Its initial commercial focus also includes shoulder-replacement planning, where faster planning could give surgeons a detailed plan before entering the operating room rather than requiring them to improvise around difficult anatomy.

Product / Service

Mango Medical is developing agentic surgical-planning AI that accepts CT scans and X-rays, reconstructs the patient’s anatomy, and recommends a procedure-ready plan covering factors such as implant sizes and surgical approach. The company describes an API-based model in which orthopedic implant companies submit imaging and receive a complete plan, with outputs delivered in seconds or minutes instead of the multiple business days associated with specialized planning teams. Its broader software vision includes patient-specific fracture reconstructions and digital planning in under three minutes.

The intended benefit is to make complex cases more predictable while reducing the surgeon’s cognitive load, planning interruptions, and dependence on intraoperative trial and error. By making planning effectively instantaneous, Mango also aims to support scenario simulation and downstream technologies such as robotic surgery and custom 3D-printed guides or implants, although the available evidence describes these as intended applications rather than proven clinical outcomes.

Market

Mango competes in AI-enabled orthopedic surgical planning and the broader medtech market for digital templating, fracture reconstruction, and personalized preoperative decision support. The opportunity is large: the company cites approximately 30 million orthopedic surgeries annually, including about 10 million joint replacements and 15 million acute fractures. PitchBook identifies OSORA medical as a competitor, while Brainlab’s TraumaCad is an established adjacent alternative offering digital orthopedic templating, implant libraries, measurement tools, automated calibration, PACS integration, and pre-surgical reports.

The company appears to be in early commercialization rather than at scale. Y Combinator lists Mango Medical as an active Winter 2026 company founded in 2024, with a three-person team, an eight-figure letter of intent from a top orthopedic company, and an ongoing pursuit of FDA 510(k) clearance. Public sources do not disclose a revenue figure; one database labels a 2025 financing record as generating revenue, so Mango should not be classified definitively as pre-revenue, but the disclosed traction is still primarily an LOI and regulatory progress rather than demonstrated recurring sales.

Founders & Leadership

Adrian KilianFounder
Founder & CEO
Jorge Padilla PerezFounder
Founder & CTO

Funding History

2025-08
Later Stage VCUndisclosed

Not disclosed

2026-01
Seed$500K

Not disclosed

2026-03
Accelerator/Incubator$500K

Y Combinator

2026-04
GrantUndisclosed

Toloka.vc

Recent News

2026-07-28
Healthcare IT Startups funded by Y Combinator (YC) 2026

Y Combinator’s 2026 Healthcare IT directory describes Mango Medical as building agentic surgical-planning AI for orthopedic surgery and delivering surgeon-ready plans in minutes instead of days.

2026-06-02funding
Tekedia Capital Invests in Pioneering Surgical Intelligence Company, Mango Medical

Tekedia Capital announced an investment in Mango Medical, which is building agentic surgical-planning AI for orthopedic surgery. The company aims to provide surgeons with procedure-ready plans in minutes rather than days.

2026-03-11partnership
Mango Medical: Taking the guesswork out of orthopedic surgeries with agentic planning

Mango Medical’s Y Combinator launch highlighted its agentic planning product for orthopedic surgery. The company invited orthopedic surgeons and implant companies to partner through an API and provide early product feedback.

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Business Model

Mango Medical’s best-supported model is B2B/API software: orthopedic implant companies use its APIs to submit patient imaging and receive automated surgical plans. Public sources do not disclose pricing or whether it charges per case, by subscription, or through enterprise contracts.

Products

Agentic orthopedic surgical-planning platformCT- and X-ray-based implant sizing and surgical-approach planning APIPatient-specific 3D fracture reconstruction and preoperative planningSurgeon-ready planning workflows for shoulder replacement and other orthopedic procedures

Tech Stack

AI foundation modelsAgentic AI / AI agentsMedical-imaging analysis of CT scans and X-rays3D imaging and patient-specific bone reconstructionMachine-learning algorithmsAPI-based delivery

Competitors

Formus Labs
AlgoSurg
CustomSurg / OrthoPlanner
Ortoma
PeekMed