Companies

Somite AI

somite.ai

Cellular Intelligence uses AI and high-throughput cellular data to design scalable cell therapies and regenerative-medicine treatments.

HQBoston, Massachusetts, United States
Employees11-50
Funding$57.1M
3 active roles
Profile 8mo agoJobs checked 4d ago
Specialization
Biotechnologyand 1 more specialization values
  • Scientific Discovery
Business
Model Developmentand 1 more business values
  • Scientific Research
Market
Life Sciences
Ecosystem
AI for science
Customers
Enterprisesand 1 more customers values
  • Researchers
More details
Organization type
Commercial Company
Ecosystem
AI for science
Business
Model Development, Scientific Research
Specialization
Biotechnology, Scientific Discovery
Market
Life Sciences
Customers
Enterprises, Researchers
Delivery models
Not classified
Revenue models
Not classified
Listing status
Not classified
Latest equity round
Not classified
Reported funding amount
$50M-$200M

About

Somite AI, now Cellular Intelligence, develops AI foundation models and proprietary capsule technology for understanding, predicting, and controlling cell behavior. It targets pharmaceutical, biotech, and cell-therapy developers, using large-scale cellular perturbation datasets—generated at substantially higher efficiency than conventional methods—to design regenerative-medicine protocols, optimize drug responses, and advance clinical cell-therapy programs.

Market

Somite AI competes in the AI-native regenerative-medicine and cell-therapy platform market, positioning itself as a foundation-model company for engineering and manufacturing human cells rather than as only a conventional cell-therapy developer. Its differentiation is the combination of proprietary capsule-generated cell-state data, embryo and virtual-cell models, and an internal therapeutic pipeline; as of January 2026, the company rebranded as Cellular Intelligence and expanded its positioning toward a universal virtual cell-signaling model. This overlaps with Cellino Bio’s AI-enabled biomanufacturing, bit.bio’s synthetic and stem-cell platforms, and Generate:Biomedicines’ AI-supported cell-therapy development.

Target Customers

Somite AI targets biopharmaceutical companies, cell-therapy developers, and translational or clinical research organizations developing scalable regenerative-medicine programs. The likely buyers are R&D, cell-therapy platform, manufacturing, and clinical-development leaders working on clinical-stage or high-throughput cell-production programs, as indicated by its OmniaBio collaboration and Novo Nordisk Parkinson’s-therapy agreement.

At a Glance

Problem

Somite AI addresses the central bottleneck in regenerative medicine: turning pluripotent stem cells into reliably pure, scalable, mature human cell types. Today, researchers largely discover differentiation protocols through slow, manual trial and error; the process can take years and tens of millions of dollars without guaranteeing a usable result. The problem is compounded by poor purity, limited manufacturing scale, and batch-to-batch reproducibility. The company has framed the gap starkly: researchers can reliably produce only about 10 cell types, versus more than 5,000 types in the human cell atlas.

The killer use case is cell replacement: manufacturing healthy tissue to replenish cells lost or damaged by disease. Somite began with somite-derived tissues such as muscle, cartilage, bone, and tendon, and targeted conditions including muscular dystrophy, diabetes, and obesity. Its most concrete current application is Parkinson’s disease, where the renamed company, Cellular Intelligence, acquired global rights to Novo Nordisk’s clinical-stage stem-cell-derived dopaminergic progenitor program.

Product / Service

The company is building an AI-native TechBio platform rather than a conventional standalone software product. Its proprietary capsule technology places cells in semi-permeable capsules and exposes them to controlled sequences of biological signals. The resulting cell-state transitions are barcoded and measured at very large scale, creating a dataset of how combinations, timing, and strength of signals steer cells toward different fates. Somite reported generating this data at roughly 1,000 times the efficiency of existing methods and scaling from a 27,000-condition pilot to more than one million sequential signal combinations in 2025.

That data trains a foundation model—originally described as DeltaStem and now presented within Cellular Intelligence’s universal virtual cell-signaling model—which predicts the protocols needed to create particular cell types. An active-learning loop uses model uncertainty to select the next experiments, allowing the system to improve as it generates therapies and manufacturing data. The practical benefit is to replace empirical protocol hunting with more predictive design, improving purity, scalability, reliability, and development speed. Public disclosures indicate that the platform is being applied to the company’s own therapeutic programs and strategic clinical collaborations, not sold as a clearly documented self-serve SaaS product.

Market

Somite competes in AI-native TechBio, virtual-cell modeling, regenerative medicine, and cell-therapy development and manufacturing. The opportunity is unusually broad: the company’s initial disease areas were associated with a roughly $250 billion therapy market, while the platform could ultimately support protocol design, disease modeling, drug-effect prediction, and production of many human cell types. Its closest competitive set is better understood as adjacent rather than identical. Cellarity uses multi-omics AI to model cellular behavior for drug discovery; Arc Institute and Tahoe Therapeutics are building large virtual-cell datasets; and Recursion is developing a computational “virtual cell.” These efforts overlap in AI-driven biological modeling, although the evidence does not identify a direct like-for-like competitor to Somite’s capsule-based sequential-signaling approach.

The company is not best characterized as a proven commercial software vendor or publicly established revenue business; available disclosures do not report product revenue. It has, however, moved beyond a purely preclinical concept. Founded in 2023, it raised more than $47 million in a 2025 Series A and reported more than $60 million raised by May 2026. After rebranding as Cellular Intelligence in January 2026, it secured global rights to Novo Nordisk’s Phase 1/2-ready Parkinson’s cell-therapy program; Novo also became an equity investor and remains eligible for milestones and royalties. The platform itself had reported in vitro and in silico proof-of-concept results and million-condition experimental validation, making clinical translation and platform validation its principal disclosed traction.

Founders & Leadership

Micha Breakstone, Ph.D.Founder
CEO and Co-Founder
Jonathan Rosenfeld, Ph.D.Founder
CTO and Co-Founder
Allon Klein, Ph.D.Founder
Scientific Co-Founder
Olivier Pourquié, Ph.D.Founder
Scientific Co-Founder and Chief Biology Officer
Cliff Tabin, Ph.D.Founder
Scientific Co-Founder
Jay Shendure, M.D., Ph.D.Founder
Scientific Co-Founder
Kristy J. Brown, Ph.D.Chief Development Officer
Nuno Mendonça, M.D.Chief Medical Officer
Jonathan AlspaughChief Strategy Officer

Funding History

2024-04
Pre-seed$5.3M

TechAviv

2024-09
Seed / pre-seed extension$4.8M

Astellas Venture Management, Montage Ventures

2025-05
Series AOver $47M

Khosla Ventures

2025-08
Strategic investmentUndisclosed

AMD Ventures

2026-05
Corporate/equity investmentUndisclosed

Novo Nordisk

Recent News

2026-01-07product_launch
Cellular Intelligence Unveils with “AlphaFold Vision” for AI-Driven Cell Therapy

GEN reported on Somite AI’s rebrand as Cellular Intelligence and its goal of building a universal virtual cell-signaling model for rational stem-cell engineering. The article highlighted the company’s capsule technology, which supports high-throughput assays and millions of time-varying signal combinations for predicting cell fate.

2025-08-20funding
Somite.ai Announces Strategic Investment from AMD Ventures to Accelerate Foundation Models for Cell Therapy

Somite.ai announced a strategic investment from AMD Ventures following its $47 million Series A. The collaboration pairs Somite’s capsule-based data-generation platform with AMD Instinct GPUs to increase compute capacity for training foundation models for cell therapy.

Active Roles

3
Boston/Engineering/56d ago
Boston/Data & Analytics/79d ago
Boston; San Francisco; Austin/Marketing/79d ago

Business Model

The company appears to monetize a full-stack biotech model rather than a disclosed subscription product: it uses its AI platform to develop and optimize proprietary cell-therapy programs, then advances them through strategic pharmaceutical agreements, equity investments, milestones, royalties, and eventual commercialization. Its 2026 Novo Nordisk transaction specifically granted Cellular Intelligence global rights to a Parkinson’s cell-therapy program, with Novo Nordisk receiving equity and eligibility for future milestones and royalties.

Products

DeltaStem, an AI platform and foundation model for producing human cells and optimizing differentiation protocolsDigital Twin of the Embryo, a computational model for simulating embryo development and guiding cell-therapy protocol decisionsSomite-derived cell-therapy programs, including beta cells, articular cartilage, satellite cells, and hematopoietic cellsSTEM-PD, a Phase 2-ready Parkinson’s disease cell therapy acquired from Novo Nordisk

Customers

OmniaBio Inc. (named cell-therapy development and manufacturing collaboration partner; not publicly identified as a customer)

Tech Stack

AI foundation modelsUniversal virtual cell-signaling modelsProprietary capsule technology for high-throughput cell-state transition dataCell-signaling and cell-differentiation datasetsComputational digital twin of the embryo

Competitors

Cellino Bio
bit.bio
Generate:Biomedicines

Key Investors

Khosla Ventures, SciFi VC, Chan Zuckerberg Initiative, Fusion Fund, Ajinomoto Group Ventures, Pitango HealthTech, TechAviv, Harpoon Ventures, Fidji Simo