Companies

Xaira Therapeutics

xaira.com

Xaira uses artificial intelligence, biological data, and drug development expertise to discover and advance transformative medicines.

HQSouth San Francisco, California, United States
Employees201-1000
Funding$1B
Valuation$2.7B
Revenue$20.2M ARR
28 active roles
Profile 3mo agoJobs checked 4d ago
Specialization
Biotechnologyand 1 more specialization values
  • Scientific Discovery
Business
Scientific Researchand 2 more business values
  • AI Research
  • Model Development
Market
Life Sciences
Ecosystem
AI for science
Customers
Enterprisesand 2 more customers values
  • Consumers
  • Researchers
More details
Organization type
Commercial Company
Ecosystem
AI for science
Business
Scientific Research, AI Research, Model Development
Specialization
Biotechnology, Scientific Discovery
Market
Life Sciences
Customers
Enterprises, Consumers, Researchers
Delivery models
Not classified
Revenue models
Not classified
Listing status
Not classified
Latest equity round
Series A
Reported funding amount
$1B+

About

Xaira Therapeutics is an integrated biotechnology company developing AI-enabled methods, biological datasets, and therapeutics to discover and advance new medicines. It ultimately serves patients and healthcare systems while pursuing partnerships with drug-development organizations; its differentiation is integrating AI research, large-scale data generation, and therapeutic development end to end.

Market

Xaira competes in the AI-native drug-discovery and integrated biotechnology market, applying AI across target biology, therapeutic design, preclinical development, and clinical development. Its differentiation is an end-to-end model that combines advanced AI research, proprietary biological-data generation, and internal therapeutic product development, rather than focusing only on a single computational chemistry or software layer. This places it alongside peers such as Recursion, Insilico Medicine, Generate Biomedicines, Isomorphic Laboratories, Exscientia, Vilya, and Valo.

Target Customers

Xaira primarily serves the pharmaceutical and biotechnology drug-development ecosystem, especially R&D leaders and computational biology, translational medicine, and therapeutic-development teams seeking AI-enabled discovery. It appears to operate mainly as an AI-native therapeutics developer that uses its platforms internally to build drug pipelines, rather than as a conventional standalone software vendor.

At a Glance

Problem

Drug discovery is a slow, expensive, and failure-prone process: bringing a new medicine to market can take more than 10–15 years and cost roughly $1–2 billion on average, with some estimates placing the fully loaded cost at $2.6 billion. The core scientific problem is threefold: identifying the disease’s causative biology, designing a molecule that can correct it, and determining which patients are most likely to benefit. Xaira’s economic thesis is that an engineered, AI-driven process can improve the probability of success while reducing development time and cost.

The main use case is discovering medicines for diseases and biological targets that conventional approaches have struggled to address. Xaira is particularly focused on previously difficult-to-drug targets and on large-molecule therapeutics, using better biological understanding and patient selection to turn otherwise inaccessible mechanisms into viable treatments.

Product / Service

Xaira is an integrated biotechnology company rather than a conventional software vendor. It combines advanced machine-learning research, large-scale biological and clinical data generation, and in-house therapeutic development. Its models are intended to operate across the full workflow, from identifying disease-relevant biology and designing drug-like molecules to selecting patients and informing clinical development. The company’s data platform spans molecular-to-human biology and uses functional genomics and proteomics to investigate causal relationships behind disease.

The platform includes AI methods for de novo protein and antibody design, including work derived from RFdiffusion and RFantibody, alongside models for biological discovery and clinical translation. Xaira’s experiments are designed to generate additional data that improves its models, creating a feedback loop between computation, laboratory work, and development. In 2026, it also launched X-Cell, a virtual-cell model trained on the X-Atlas/Pisces genome-wide perturbation dataset, which contains 25.6 million perturbed single-cell transcriptomes. The intended benefit is a repeatable discovery engine that produces a pipeline of differentiated medicines, including therapies against targets that have resisted traditional approaches.

Market

Xaira competes in the emerging AI-native drug-discovery and next-generation biopharmaceutical market. Its closest public peers include Recursion, which applies AI to cellular imaging and drug discovery; Insilico Medicine, which describes an end-to-end AI drug-discovery pipeline; and Isomorphic Labs, which develops predictive and generative AI for designing molecules and modeling biology. Unlike a pure platform company, Xaira’s stated model is to use its technology internally to discover and develop its own medicines across multiple modalities.

The company launched with more than $1 billion in committed capital, an unusually large financing base for an early biotech, and has since demonstrated platform traction through its biological datasets, virtual-cell work, and an active pipeline of de novo biologics across multiple indications. However, its public disclosures remain light on named disease programs and candidates, and 2026 reporting described partnership activity as focused on building preclinical models and validating the pipeline. The evidence does not establish product revenue or an approved commercial medicine, so Xaira is best characterized as a well-funded, pre-commercial or pre-revenue biotech whose value remains tied to converting its AI and data platform into clinical and ultimately commercial assets.

Founders & Leadership

Marc Tessier-LavigneFounder
Chairman & Chief Executive Officer
David BakerFounder
Scientific Advisor
Arvind RajpalFounder
Executive Chairman / Investor
Hetu KamisettyFounder
Chief Technology Officer
Joe Watchwell WatsonFounder
Co-Founder
Don KirkpatrickFounder
Co-Founder (current operating title not identified)
Ci ChuChief Discovery Officer
Paulo FontouraChief Medical Officer
Debbie LawChief Scientific Officer
Julia TranChief People Officer
Bo WangChief AI Scientist
Rachel LaneSenior Vice President, Business Development and Operations
Ian McCafferySenior Vice President, Translational Science and Early Clinical Development

Funding History

2024-04
Launch financing (Series A per Crunchbase; classified as Series D by Tracxn)More than $1B

ARCH Venture Partners, Foresite Capital, Foresite Labs

2025-08
Series A$800M

Recent News

2026-10-02other
Xaira reveals antibody platform and initial pipeline

Xaira disclosed its antibody platform and an initial look at its pipeline in a company news item. Xaira’s homepage dates the item to October 2, 2026.

2026-09-02other
Xaira wins 2026 Fierce AI Innovation Award for Preclinical Development

Xaira Therapeutics won the 2026 Fierce AI Innovation Award in the Preclinical Development category. The recognition cited Xaira’s X-Atlas/Pisces and X-Cell technologies as foundational to its AI-driven drug-discovery approach.

2026-01-29other
How AI is Driving Drug Discovery: Xaira Therapeutics’ Marc Tessier-Lavigne

Goldman Sachs interviewed Xaira co-founder, chairman, and CEO Marc Tessier-Lavigne about how AI is being used to drive drug discovery and development.

Active Roles

28
South San Francisco, California, United States/Other/6d ago
South San Francisco, California, United States/Other/12d ago
South San Francisco, California, United States/Operations/14d ago
South San Francisco, California, United States/Operations/18d ago
South San Francisco, California, United States/Operations/18d ago
South San Francisco, California, United States/Engineering/21d ago
South San Francisco, California, United States/Operations/28d ago
South San Francisco, California, United States/Other/32d ago
South San Francisco, California, United States/Other/35d ago
Seattle, Washington, United States; South San Francisco, California, United States/Data & Analytics/40d ago
South San Francisco, California, United States/Other/40d ago
South San Francisco, California, United States/Engineering/46d ago
Seattle, Washington, United States; South San Francisco, California, United States/Engineering/52d ago
South San Francisco, California, United States/Other/53d ago
Seattle, Washington, United States/Data & Analytics/60d ago
South San Francisco, California, United States/Engineering/62d ago
South San Francisco, California, United States/Sales/66d ago
South San Francisco, California, United States/Operations/66d ago
South San Francisco, California, United States/Finance/66d ago
South San Francisco, California, United States/Engineering/80d ago

Business Model

Xaira does not publish a detailed pricing model. The evidence supports a product-led biotechnology model: it develops proprietary AI-enabled drug-discovery capabilities and therapeutics, with potential commercial revenue from medicines and partnerships or licensing deals rather than a standalone software subscription.

Products

End-to-end predictive and agentic AI models for drug discovery and developmentBiological data platform spanning molecular-to-human data, functional genomics, and proteomicsComputational biology, molecule-design, and de novo protein-design capabilitiesTherapeutic product development across multiple modalitiesX-Atlas public data/model assets, including Orion Viewer and Pisces

Tech Stack

Machine learning and AI/MLPredictive and agentic AI modelsComputational biology and biological discoveryDe novo protein designFunctional genomics and proteomicsMultidimensional biological-data generation and integration

Competitors

Recursion
Insilico Medicine
Generate Biomedicines
Isomorphic Laboratories
Exscientia
Vilya
Valo

Key Investors

Arch Venture Partners, Foresite Capital, Lux Capital, SV Angel, Sequoia Capital, Menlo Ventures, NEA Partners