Companies

Nanograb

nanograb.com

Nanograb uses generative AI to design nanoparticles for cell-selective drug delivery.

HQSan Francisco, California, United States
Employees1-50
Jobs checked 4d ago
Specialization
Biotechnologyand 1 more specialization values
  • Scientific Discovery
Business
Software Applicationsand 1 more business values
  • Scientific Research
Market
Life Sciences
Ecosystem
AI for science
Customers
Enterprisesand 1 more customers values
  • Researchers
More details
Organization type
Commercial Company
Ecosystem
AI for science
Business
Software Applications, Scientific Research
Specialization
Biotechnology, Scientific Discovery
Market
Life Sciences
Customers
Enterprises, Researchers
Delivery models
Hosted Software
Revenue models
Subscription
Listing status
Not classified
Latest equity round
Pre Seed
Reported funding amount
Not classified

About

Nanograb builds an AI-driven computational drug-discovery platform that designs targeted non-viral gene-therapy vectors and nanoparticles for cell-selective drug delivery. It focuses on pharmaceutical-industry applications, differentiating through generative AI and computational design of highly targeted treatments.

Market

Nanograb competes in AI-enabled drug discovery and nanomedicine, particularly targeted non-viral gene and genetic-medicine delivery. Its differentiation is the use of generative AI and a multivalent physics engine to select combinations of small peptide binders, with the stated goal of minimizing off-target binding and reaching previously inaccessible tissues; competitors use adjacent approaches such as AI-designed polymer nanoparticles, targeted lipid nanoparticles, or integrated RNA-delivery platforms.

Target Customers

Nanograb primarily targets biopharma companies, with principal scientists and business leaders as likely partnership buyers. Its applications are aimed at teams developing therapies for cancer, degenerative, infectious, and neurological diseases.

At a Glance

Problem

Drug delivery is often limited less by the medicine itself than by getting it to the right cells without harming healthy tissue. Nanograb says 70% of drugs fail in clinical trials because of poor targeting, while side effects force developers to use lower doses; more precise delivery could enable smaller, more effective doses. The company’s central pain point is the absence of platforms that can reliably direct therapies to exactly the desired location in the body.

The clearest use case is cell-selective delivery of genetic medicines, particularly for difficult targets such as cancer, neurological conditions, infectious diseases, and previously inaccessible tissues. In these applications, a therapy that reaches the right cells while minimizing off-target binding could materially improve efficacy and tolerability.

Product / Service

Nanograb is building an AI-enabled computational drug-discovery platform for targeted, non-viral gene-therapy vectors. It designs combinations of small peptide binders attached to nanoparticles, using generative AI and a multivalent-physics engine to predict which combinations will bind to specific cells or tissues while minimizing binding to the wrong targets.

The apparent delivery model is partnership-led: Nanograb supplies the computational design and supporting science to biopharmaceutical developers rather than selling a finished medicine directly. Its stated benefit is a scalable way to create more precise nanoparticle delivery systems, potentially allowing drugs to reach new parts of the body, reduce side effects, and support on-demand development of therapies for multiple diseases.

Market

Nanograb sits at the intersection of AI-powered drug discovery, nanomedicine, biotechnology, targeted drug delivery, and gene-therapy infrastructure. Third-party company profiles identify Isomorphic Labs, Absci, and Generate Biomedicines as possible competitors, although these are broader AI-drug-discovery peers rather than necessarily direct competitors in multivalent nanoparticle targeting.

The company was founded in 2023, participated in Y Combinator’s Summer 2023 batch, is listed as active, and has a five-person team. Its launch materials report proof-of-concept data in vitro and in vivo and say it is seeking partnerships with biopharma companies. Commercial traction remains unclear: a public PitchBook profile labels listed deals as generating revenue but leaves its current-revenue field blank, so Nanograb is best characterized as an early-stage platform with technical validation and partnership ambitions rather than a company with publicly established commercial scale.

Founders & Leadership

Debesh MandalFounder
Co-Founder and CEO
Christopher LauFounder
Co-Founder and Product Lead
Shanil PanaraFounder
Co-Founder and In Silico Lead

Funding History

2023-01
Pre-Seed$500K

Y Combinator

Recent News

2026-09-26product_launch
Nanograb announces NGX1, a platform for targeted mRNA delivery

Nanograb announced NGX1, a platform for designing multi-peptide targeted lipid nanoparticles (tLNPs), describing it as a navigation system for mRNA drugs. The announcement says it uses short peptides rather than antibodies or other biologics to address scale-up challenges.

2026-09-02funding
Nanograb raises $26M

Nanograb reported that it had raised $26 million from investors. The public listing does not specify the financing round type or identify the investors.

2026-09-02partnership
Nanograb closes $1B in AI partnerships

Nanograb reported closing $1 billion in AI partnerships through multi-year agreements with Amgen, Pfizer, and the NIH. The partnerships relate to Nanograb’s computational drug-discovery and targeted gene-delivery technology.

2026-08-12funding
Nanograb receives Innovate UK project funding for AI-based drug-delivery research

Nanograb was named as one of nine projects receiving Innovate UK funding under a competition developing non-animal approaches for medicines development. Its project uses AI to predict lipid nanoparticle pharmacokinetics and biodistribution from formulation data, aiming to reduce reliance on dedicated non-human primate studies.

2026-01-31product_launch
Start-up Nanograb launched

The Stevens Group announced Nanograb’s launch as a computational drug-discovery company using AI to generate combinations of binders for precise drug-delivery targeting. The company stems from an academic collaboration between the Stevens Group and Dr. Stefano Angioletti-Uberti’s group.

2025-09-23other
Sanofi × Nucleate: AI Meets Biotech in Paris

A Sanofi–Nucleate event at La Maison Sanofi headquarters in Paris listed Nanograb among the companies pitching at the event. The evidence supports Nanograb’s participation, but does not establish a formal commercial partnership with Sanofi or Nucleate.

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Business Model

Nanograb appears to operate as a SaaS-based computational drug-discovery platform, generating recurring revenue or ARR. The available evidence does not specify pricing tiers or separately identify licensing and partnership revenue.

Products

AI-designed multivalent nanoparticles for cell-selective drug deliveryTargeted, non-viral gene-therapy vectors using combinations of small peptide binders attached to nanoparticlesA computational platform for designing next-generation targeted therapies

Tech Stack

Generative AI for nanoparticle designMultivalent physics engineSmall peptide-binder combination designNanoparticle-based, non-viral gene-delivery systems

Competitors

Nanite
Capstan Therapeutics
Evox Therapeutics
Orbital Therapeutics