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America is facing an addiction and mental health crisis. We're building a suite of AI agents to automate away the tasks that occupy half of the time and resources of behavioral health clinics—documentation, compliance, audits, and more. We save time, money, and mental bandwidth so that clinicians can stop chasing insurance reimbursements and go back to saving lives.
Commercial CompanyAgentsSoftware ApplicationsHealthcareSmall BusinessesEnterprisesHosted SoftwarePre Seed
Petrarch acquires datasets from legacy businesses and declining industries and prepares them for use in AI. It cleans and anonymizes the data, then sells the resulting datasets to AI companies building models for physical-world applications.
Commercial CompanyMarketplace OperationData ProvisionData EngineeringManufacturing
PgDog is an application for sharding PostgreSQL. It understands SQL and can distribute queries automatically between databases. It's built for managed databases, like AWS RDS, and doesn't require any changes to application code or schema. In addition to sharding, PgDog is a load balancer and pooler, so it can act as a replacement for PgBouncer, RDS Proxy, and other Postgres scaling products. It brings the simplicity and performance of HTTP load balancing to the database. Built from the experience of sharding Postgres at Instacart during peak growth in 2020, PgDog is the answer to the old question: does Postgres scale? It does now.
Commercial CompanySoftware ApplicationsData Engineering
Phase Biolabs makes carbon negative solvents and electro-fuels from carbon dioxide (CO2) using fermentation. You can read more about what we are building in our Hacker News article: https://news.ycombinator.com/item?id=30557288 Phase Biolabs is also supported by Bill Gate's Breakthrough Energy Foundation via their Innovator Fellowship program.
Commercial CompanyHardware ManufacturingScientific ResearchBiotechnology
Photonium is building software to automate optical system design. We supercharge optics experts with intelligent tooling to reduce costs and deliver faster. We handle the full design stack — from optimization, verification, sourcing, to prototyping — for AR/VR, quantum, biotech, metrology/chip fab, LiDAR, and more.
Commercial CompanyAI for scienceSoftware ApplicationsConsultingProfessional ServicesSemiconductorsManufacturing
Pingo AI is an AI language learning app that helps users build fluency through speaking. It immerses learners in realistic dialogues and personalized lessons with an AI tutor who sounds like a native speaker. Our goal is to make learning languages as simple as daily conversations with Pingo — a companion who understands your goals, remembers your progress, and keeps you motivated.
Commercial CompanyApplicationsSoftware ApplicationsSpeechEducationConsumersStudents
Piris Labs offers a full-stack inference service that eliminates the AI data movement bottleneck. By pairing proprietary photonic hardware with a vertically optimized software stack, we minimize the "memory wall" associated with expensive GPUs. This allows us to deliver the same performance as traditional clusters at a fraction of the cost. Our technology improves effective FLOP utilization and reduces latency, finally making the unit economics of trillion-parameter models sustainable. Founded by a team of MIT physicists and Meta AI experts.
Commercial CompanyInferenceHardware Manufacturing
Platus delivers fast, reliable legal infrastructure with a no-code platform and API, designed to support SMBs with instant access to notarization, legal drafting, e-signing, and workflow automations. Our solution removes the high costs and slow processing of traditional legal services, by empowering businesses to seamlessly manage compliance and legal tasks.
Commercial CompanyAgentsSoftware ApplicationsLegal ServicesCross IndustrySmall BusinessesDevelopers
PlayerZero offers an AI-powered platform for predictive software quality, enabling agentic debugging and code simulations to help engineering teams fix, learn from, and prevent defects across large codebases, with a focus on enterprise-scale software development and AI-native tooling.
Commercial CompanyAgentsSoftware ApplicationsSoftware Development
Plena is the AI operating system for specialty medical practices. We automate the administrative workflows that keep clinics running — referrals, fax intake, scheduling, procedure compliance, and collections — end to end, across all the systems a practice already uses. Unlike point solutions that cover a slice of the problem, Plena becomes the operating layer across the entire practice, connecting the systems, teams, and workflows that keep it running. In 10 months we've grown 17x and crossed seven figures in committed ARR across six specialties and eight states, with 80% of growth through word of mouth.
Commercial CompanyApplicationsSoftware ApplicationsHealthcare
Plexe builds predictive ML models from a problem description. It connects to data sources, conducts experiments, evaluates and deploys the models to an API endpoint.
Commercial CompanyAgentsProfessional ServicesSoftware ApplicationsCross IndustryEnterprisesProfessional ServicesOn Premise Software
First regulated exchange for compute
Commercial CompanyFinancial ServicesMarketplace OperationFinancial ServicesSoftware DevelopmentEnterprises
Pointhound makes it easy to earn and redeem your credit card points for free flights. We're driven by our mission to make the world more accessible through travel.
Commercial CompanySoftware ApplicationsData ProvisionTransportationFinancial Services
Powder is an AI tool that helps wealth advisors rapidly create sales proposals that are personalized for each prospective client. Using LLMs, Powder is able to automate a series of manual tasks such as understanding documents and conversations to create mind-blowing analysis that builds immediate trust. Powder has 3 main features to automate sales workflows - 1. Brokerage, tax and estate document parser thats fast and accurate. 2. Meeting notetaker thats able to capture personalized insights. 3. Portfolio analysis tool that optimizes portfolio returns, risk and fees. Our app saves hours of time and creates a pinpoint proposal that lifts a firm's ability to win new business.
Commercial CompanyApplicationsSoftware ApplicationsFinancial ServicesSmall Businesses
Furniture companies spend millions and months each year on photoshoots or CGI to create product images as these visuals are crucial for driving sales. Presti offers a faster and cheaper solution powered by generative AI. Unlike other generative AI tools, our core model is optimized for furniture products and includes multiple features tailored to the unique needs of furniture industry. We have 100 paying B2B users with a 10% growth week over week. We raised a $3.5M seed round
Commercial CompanyApplicationsSoftware ApplicationsContent ProductionProfessional ServicesRetail
ProhostAI is building an AI Property Manager for short-term rental hosts on Airbnb and other platforms. Our team consists of an ex-Airbnb Staff Data Scientist and Dropbox Sr Software Engineer who are also Superhosts with 9 properties worth $15M making $1.5M/yr.
Commercial CompanyAgentsSoftware ApplicationsHospitalityReal Estate
Proliferate gives coding agents production-grade infrastructure- sandboxed environments, event triggers, and verification workflows- so they can ship code end-to-end, not just write it.
Commercial CompanyAgentsAgent ToolingSoftware ApplicationsSoftware Development
PromptArmor provides security and compliance tooling for applications built on large language models. It detects and mitigates LLM-specific threats such as prompt injection and data leakage, and supplies AI threat intelligence so companies can deploy LLM applications safely.
Commercial CompanyApplicationsSoftware ApplicationsSecurityAI GovernanceCross IndustryEnterprises
Docs are integral to a great customer experience, but managing them is a challenging, multi-team effort. The most successful companies recognize that fantastic docs drive adoption and bad ones cause customers to churn. Promptless is used by fast-growing startups and Fortune 500 enterprises alike to automatically update docs based on feature releases, support tickets, internal Slack conversations, and more. Promptless is designed to be flexible—it can integrate with any docs platform, be triggered automatically from many workflows, and can pull in context from any internal knowledge source. With Promptless, documentation becomes a strategic advantage for growth, not a bottleneck or a liability.
Commercial CompanyApplicationsSoftware Applications
ProvenMetal manufactures the fastest circuit boards in the United States. Domestic circuit board manufacturing is slow and expensive, and while reshoring is happening, the supply chain isn't there yet. We automate the bottlenecks - part procurement, DFM review, and assembly - delivering circuit boards in days instead of weeks.
Commercial CompanyHardware ManufacturingProduct ManufacturingManufacturing
Proximitty is the first truly AI-native loan management system. We build unified lending data layers and personalised risk scoring models to power AI agents that dynamically learn, adapt and increase collection rates for banks, credit unions and fintechs, while automating complex servicing workflows with no-code browser agents. Trusted by publicly traded fintechs and banks globally.
Commercial CompanyAgentsSoftware ApplicationsProfessional Services
Qeen.ai is a Dubai-based GenAI-native platform delivering autonomous AI-powered solutions for ecommerce conversion, revenue, and experience, including dynamic content generation, a growth marketing agent, and automated optimization across ads and site experiences.
Commercial CompanyAgentsSoftware ApplicationsProfessional Services
Quill Bills is a medical billing company that works with healthcare providers to significantly lower billing costs and fight every denial.
Commercial CompanyApplicationsProfessional ServicesSoftware ApplicationsHealthcare
Quivr is an AI-powered customer support tool that helps teams draft responses, automate replies, and resolve tickets directly inside platforms like Zendesk or other helpdesk solutions. The platform augments agent productivity by reducing repetitive work and accelerating resolution time.
Commercial CompanyApplicationsSoftware ApplicationsCross IndustryEnterprises
Rally is a User Research CRM that makes it easy for teams to do research with their users. By automating outreach, scheduling, incentives, and participant management, Rally replaces messy spreadsheets and disjointed tooling, saving teams hours each week.
Commercial CompanySoftware ApplicationsCross IndustryEnterprisesResearchers
Rapidfolio helps banks and fintechs fully automate back-office workflows like fraud investigations, KYB/KYC and loan underwriting, with accuracy and auditability. Built by fintech founders and operators, Rapidfolio is on a mission to ensure banks and fintechs scale their customer base without adding another back-office head count.
Commercial CompanyAgentsSoftware ApplicationsAgent ToolingSecurity
At Raven, we are building AI assistants for manufacturing plants which can offer intelligent assistance for day-to-day operations like training, job planning, troubleshooting, reporting and also helps with real-time analytics — all while seamlessly integrating with your existing systems. We’re taking decades of manufacturing expertise and combining it with AI to solve real operational problems. We’re a small, focused team working to make industrial operations safer, smarter, and more efficient.
Commercial CompanyApplicationsSoftware ApplicationsData Engineering
Redactive provides an enterprise AI data security platform that secures AI-driven data access by enforcing granular, context-aware permissions across unstructured data, including across knowledge bases. It differentiates itself with capabilities like Permissions Assurance and Permissions Enforcement to fix misconfigurations at scale and prevent data leaks from shadow AI usage, enabling secure AI adoption in regulated enterprise environments. Target customers are large organizations adopting AI across industries; the product is positioned as a horizontal AI data-security platform and developer tooling for AI applications.
Commercial CompanyApplicationsSoftware Applications
Refactor works closely with large organizations across healthcare, retail, and logistics to safely tackle their most ambitious AI use-cases in record time. We focus on building autonomous systems that call, click, and navigate legacy software systems. We have worked with companies serving tens of millions of customers and with $50B+ annual revenue.
Commercial CompanyAgentsProfessional ServicesSoftware Applications
Reflexivity is an analytics and artificial intelligence platform that provides investment research tools for institutional investors, hedge funds, and banks. It combines AI-driven insights, knowledge graphs, and scenario analysis to surface actionable signals from financial data sources. The platform is designed to speed up research workflows for asset management and investment decision-making.
Commercial CompanyApplicationsSoftware Applications
Regie.ai provides RegieOne, an AI-native sales engagement platform that automates outbound prospecting and workflow orchestration with AI Agents and human reps, enabling scalable, personalized outreach for B2B teams; monetizes through SaaS subscriptions and add-on AI capabilities.
Commercial CompanyAgentsSoftware ApplicationsCross Industry
RentFlow is the first ‘Buy Now Pay Later’ platform for commercial rent. In the US alone, ~ 50% of small & medium businesses are behind on their rent. RentFlow is the first AI-powered platform to end the late rent cycle for businesses: For landlords: Rent is paid in full and on time every month, at no extra cost. Cut the collections hassle. For businesses: Rent is split into smaller, revenue-synced installments. Match fixed costs to real cash flow year-long. No late rent. Just perfect timing on both sides.
Commercial CompanyApplicationsFinancial Services
Rescript helps regulatory compliance and advocacy teams effortlessly track the constant stream of legal developments to always stay ahead and compliant. Rescript intelligently scans the web and analyzes regulatory changes and emerging issues, enabling teams to respond proactively and efficiently. Rescript helps Fortune 100 compliance officers juggling multi-state regulations, lobbyists tracking late-night amendments on the Hill, and trade association analysts scanning dozens of agencies at once. We’re profitable and backed by seed funding from YC, General Catalyst, and Floodgate.
Commercial CompanyApplicationsSoftware Applications
Resistant AI develops AI-powered software for fraud detection and financial crime prevention. It provides tools for document verification, transaction monitoring, and defense against fraud across the customer lifecycle (onboarding, lending, tenant screening, and claims processing). The company targets banks, fintechs, and merchants, monetizing via enterprise software licensing and related services, with a focus on explainable AI and defense-in-depth.
Commercial CompanyApplicationsSoftware Applications
AI employees for home services and trades businesses. We automate the back office so field crews can focus on the actual work. Trades businesses (HVAC, plumbing, electrical, collision repair, roofing) run on legacy software and "glue" employees: people whose entire job is clicking through systems, copy-pasting between tools, and managing inbound volume across channels. A collision shop has one person generating estimates in CCCOne, another chasing parts vendors, another answering calls and Yelp messages, another doing invoices in QuickBooks. None of that requires a human. We build proactive background agents that run these operations autonomously -- quoting, estimating, procurement, insurance coordination, scheduling, follow-ups -- on top of the software these businesses already own. We started as an AI consulting firm talking to businesses across every industry. After a month, the pattern was obvious - trades and field services had the most "glue work" and the least tech sophistication to solve it themselves. Every shop we walked into had 2–4 people doing work that software should be delivering as an outcome, not just enabling. Our GTM is direct to operators and through PE-backed roll-ups, who are actively looking for margin improvements across their portfolio companies. If this is of interest, please reach out arushi@ressl.ai
RetroFix is an automation platform designed to be extremely intuitive to use, making it much easier and faster to automate manual work. To create or modify workflows you can describe them in natural language and our agent will create them end-to-end for you. We allow you to connect with 2000+ applications and use our pre-built actions for your workflows. In the case we don't have a pre-built step, our agent can instead write code to access the full APIs of all the apps we integrate with.
Commercial CompanyAgentsSoftware ApplicationsAgent Tooling
Revion is building the operating system for Automotive Retail. Our first product helps Technicians automate administrative work, which drains 30-40% of their day. With Revion, Auto Retailers can service more vehicles and drive more high-margin Revenue.
Commercial CompanyApplicationsSoftware ApplicationsSpeechTransportation
Navigating chronic illness is an isolating and lonely process which ultimately reduces medical adherence and adversely impacts outcomes. There are over 100 deadly chronic conditions as 1 out of 2 Americans is currently living with at least 1 chronic condition. The US healthcare system has over $1 trillion dollars in direct costs. Medical adherence rates for therapeutic programs and medicine are only 50% because patients feel lonely, isolated, and unsupported in their chronic illness journey. Reviving Mind is an in-network telehealth provider that improves clinical outcomes and program adherence for the senior medicare and medicare-advantage population that is plagued with loneliness and chronic illness. This is done through a novel and proprietary clinical program and technology platform that integrates virtual, private, curated, and professionally led groups that scale up to 8-patients with individualized and goal oriented lifestyle medicine coaching that is automated but managed by a licensed provider. Scaling rapidly across the United States.
Commercial Company
$8 trillion dollars of market cap needs to know what the FDA thinks. Rhizome AI makes that happen. Users ask a question and get an answer backed by up to 1,000 documents, where each statement has a citation. The data is pulled from terabytes of authoritative regulatory & clinical databases. Chetan started his career as a research engineer, but quickly realized he enjoyed building more than research. He joined EvolutionaryScale as their sole founding product engineer, launching their developer-scientist platform and scaling to tens of thousands of users and billions of API calls. He was also #16 at Instabase helping banks with document & imaging processing, closing $7m as the technical lead. Being so plugged into the AI world, he saw lots of AI drug discovery companies, but very few AI companies focused on bringing those drugs to market. Talking to people, it quickly became clear that a big, expensive barrier was understanding FDA thinking. Rhizome’s first product, Rhizome Ask, went from launch to six-figures in revenue during 2025.
Commercial Company
Rhythms builds an AI‑powered operating system that maps and automates the repeatable rhythms of high‑performing teams. The platform targets mid‑to‑large enterprises seeking to align strategy with daily execution, especially those with hybrid workforces. It competes in the business productivity and SaaS market against OKR and workflow tools, positioning itself as the first AI‑native operating system that identifies productive work patterns and offers automated playbooks. Revenue is generated via a subscription‑based B2B SaaS model. Differentiators include deep AI analysis of team behavior, integration with existing tools, and a focus on “rhythms” rather than isolated task management, promising higher productivity through data‑driven automation.
Commercial CompanyApplications
Geopolitical conflicts and natural disasters frequently expose the vulnerability of the American chemical industry. The reason? Production is centralized and fossil fuel-dependent. The solution? Localized production using an undervalued resource: biogas. The US produces enough biogas to make over $20 bn/y worth of chemicals, but 60% is wasted in low-margin applications or flared altogether. Rise Reforming is commercializing a modular process to transform this underutilized biogas on-site into cheap, supply-secure chemicals. Our beachhead market is dimethyl ether (DME), used as an aerosol propellant and a low-carbon fuel additive in propane. Our target market is methanol: an established billion $ chemical and the future of low-carbon shipping. We're doing our pilot project at a Chicagoland wastewater plant. This will be the first wastewater biogas-to-methanol demo in the Americas. We're hiring for a senior chemical process engineer. Apply here: https://www.ycombinator.com/companies/rise-reforming/jobs/wJ9Q9nv-senior-chemical-process-engineer
Commercial Company
River Markets is the prime brokerage for prediction markets. We aggregate every major event-contract venue into one account, giving professional traders best execution, portfolio and order management systems, and a unified API.
Commercial CompanyFinancial ServicesSoftware ApplicationsFinancial ServicesEnterprises
Easily build & scale AI agents, functions, stateful services, and more. Open-source & self-hostable.
Commercial CompanyAgentsCompute HostingAgent ToolingSoftware ApplicationsDistributed Computing
Robby is an AI growth engine for home services businesses that uncovers revenue opportunities and collects additional data from every technician visit. Our AI combines customer and third party data to generate dozens of new leads every day, and then arms the technicians with talking points to increase close rates, giving GMs a single command center to manage and drive revenue. We have several paying customers that are each uncovering 6 figures in additional revenue opportunities every week. On our first day of launch, we helped close $40k in new business within an hour. Our team has spent the last few months riding along with dozens of technicians and shadowing every position in the office to best understand the industry. We're also studying for the EPA 608 exam to become certified technicians ourselves. Vineet and Feroze have both built critical products and infra at prominent startups (Ironclad, Porter, Affinity, Uber, Cloud Health Systems). Joe previously consulted PE firms on software acquisitions and led home services growth projects at Bain. We all met at Harvard Business School, and dropped out to work on Robby full-time.
Commercial Company
RoboDock builds robots that automate depot operations, like charging and vehicle checks, for electric and autonomous vehicle fleets. We turn fleet depots from manual sites into self-running systems that lower operational costs and increase vehicle uptime.
Commercial CompanyPhysical AIRobotics SystemsHardware ManufacturingRobotics
Rownd helps enterprises in regulated industries build and deploy AI applications with our open-core model, providing production-ready components for RAG systems, model fine-tuning, and prompt engineering that run entirely on-premise while maintaining complete data sovereignty. With a powerful CLI and YAML configs, teams can create differentiated AI products without vendor lock-in or ML expertise, ensuring compliance and cost control that cloud-only solutions can't match.
Rulebase builds AI coworkers that help banks and fintechs review 100% of customer interactions in real time. Our agents flag compliance breaches, high-risk issues, and quality gaps across calls, chats, and emails — then route them to the right teammates. The result: up to 30% fewer escalations and QA cycles reduced from hours to minutes.
Commercial CompanyAgentsSoftware ApplicationsFinancial ServicesEnterprisesHosted SoftwareSeed
Edge AI is inevitable, but shipping it is painful: every device class behaves differently, runtimes vary, models are huge, and performance collapses under memory/power constraints. RunAnywhere turns that into an enterprise-ready workflow: one SDK to run models on-device, plus a control plane to manage models, enforce policies, and measure outcomes across thousands of devices.
Commercial CompanyInferenceSoftware ApplicationsMultimodal ModelsSoftware DevelopmentDevelopers
Ryvn provides the devtools and infrastructure to easily deploy any workload, on any cloud, and on-prem. Run apps in your own cloud and offer Bring Your Own Cloud (BYOC) to your customers in minutes, with built-in observability designed for sensitive industries.
Commercial CompanySoftware ApplicationsDistributed ComputingSoftware DevelopmentDevelopers
At SAMMY, we do knowledge. Not “find me every time [thing] was mentioned,” but real knowledge. A compliance or legal update comes in — where does it apply, how does it affect our processes, and what should we do next?A process changes — which related processes need updating? Update them for me. We’re trusted by some of the largest companies in the world to power their knowledge, because without knowledge, AI is just a bull**** exacerbator.
Commercial CompanyApplicationsSoftware ApplicationsLegal ServicesCross IndustryGovernment