Electric Air is a tech-enabled contractor for heat pump installations that cuts costs by 60%. Heat pumps are the most efficient way to heat American homes with a $53B annual market opportunity.
Elementary enables data teams to detect problems in their data before their users do. An open-source solution that any data engineer can deploy in minutes without sharing sensitive data.
Elessar boosts engineering productivity by integrating with your existing ecosystem of tools to automatically generate changelogs, streamline communications, and provide AI-powered reporting to engineers & managers.
Elevate is bringing AI to private equity-backed roll-ups. For example, one of our customers is Guardian Restoration Partners, which is backed by Alpine Investors, the leading roll-up focused private equity firm. In three months, we integrated 10 acquisitions and enabled them to pilot AI agents built on top of our data warehouse. We know this problem personally. Before Elevate, Scott was a Vice President at a $15B private equity firm where he was leading a roll-up. Steve and Jeff are both software engineers with backgrounds across finance, big tech, and start-ups. The founding team has been friends for over a decade from their Duke undergraduate days.
We provide US based USD deposit accounts that sit with a licensed banking partner. Elevate's FDIC-insured USD accounts offer ACH, wire inbound and outbound payments, and a free Mastercard debit card. Our regional payout partners enable our users to send their money back home at very low cost. We're targetting non-US residents in emerging markets who struggle to get paid in USD.
Ellipsis will help your team merge code 13% faster. Ellipsis is an AI developer tool that automatically reviews code and fixes bugs on pull requests. It uses LLM agents to catch logical errors, security issues, and can even enforce a team's style guide. The coolest part is that after Ellipsis identifies an issue, developers can tag @ellipsis-dev to have Ellipsis implement the fix. Internally, Ellipsis actually executes the code it generates, just like a human does. As a result, we allow developers to generate working, tested code directly from GitHub/GitLab.
Elodin creates flight software, simulations, and hardware for drones, satellites, and defense.
We automate complex, regulated operations in financial services—no APIs, no engineering required. We hit $500K ARR in just four weeks because customers deploy instantly. Our AI Operator learns by observing existing workflows and SOPs, securely controlling browser and desktop applications to automate up to 96% of tasks.
We're building the equivalent of 401ks for Pakistan as the first step towards building a comprehensive wealth management platform for the country.
Elyos AI is a fully autonomous AI Agent, built specifically for trades and field services businesses.
Over 80% of maternal mortalities were preventable with earlier intervention. Currently, doctors miss >50% of moms who have life-threatening complications and wait until labor to start doing manual risk assessments, at which point it's too late. Elythea's proprietary ML models catch life-threatening obstetric complications (like postpartum hemorrhage, preeclampsia/eclampsia, emergency c-section, preterm labor, and more) as soon as the first visit. We automatically analyze relevant demographic and clinical risk factors, flag high-risk patients, and provide evidence-based interventions, giving doctors months in advance to intervene and prevent complications from ever happening. Our global clinical studies have shown that we can catch 3x more complications than clinical judgment 10x sooner.
Embedder is a coding agent that can write, test, and debug firmware.
At Ember, we're tackling one of healthcare's most costly and overlooked challenges: the massive inefficiency in clinical documentation and revenue cycle management. Medical practices lose billions annually due to incomplete documentation, missed billing opportunities, and denied claims - issues that stem from antiquated systems that force clinicians to choose between patient care and paperwork. We combine ambient listening technology with deep understanding of medical billing requirements to eliminate the administrative burden that plagues healthcare providers.
Ember builds hardware and system observability tools for robots and IoT devices. Founded by former Tesla Autopilot engineers, we help hardware teams catch failures early, reduce downtime, and iterate with confidence from prototype to scale.
Agent-first development environment. Emdash enables engineering teams to develop software faster, by running multiple coding agents in parallel. We're an open-source and provider-agnostic desktop application.
Vocational training programs and workforce management software for government agencies looking to create high-paying jobs and up-skill their low-income and justice-involved citizens out of poverty.
Emergence AI builds autonomous AI agents and an orchestration platform to automate, optimize, and scale enterprise workflows across diverse tasks and domains; customers are enterprises seeking to improve productivity and integration with existing tools.
Emigre is the fastest and the only end-to-end digital Indian banking solution for Indian expats (Non-Resident Indians) so they can support their families back home, shop on Indian websites, and invest in Indian stocks and real estate.
Emobi is a unified legal, financial, and technical infrastructure that delivers seamless, secure, and reliable EV charging across networks—powering apps, fleets, and automakers while maximizing charger utilization. Our secure, fully automated charging technology, JustPlug, works instantly with no special hardware, software, or setup, making EV charging effortless. With 122,000+ EV chargers integrated across the U.S. and Canada, Emobi is recognized as the largest EV charging ecosystem in North America. Backed by two provisional patents and 15+ enterprise customers, Emobi's technology is also trusted by the Department of Energy (DoE) and the Department of Transportation (DoT). To learn more, visit www.emobi.ai.
Don't die of heart disease. While heart disease is the #1 killer worldwide, 80% of heart disease is preventable. Empirical's program starts with an advanced lab test with 100+ biomarkers, including ApoB, Lp(a), inflammation, and more. Then, we help you model your lifetime risk of heart disease and generate a plan to reduce your risk to an optimal level. Then we help you achieve that plan. Empirical is licensed, registered, and insured to deliver real medical care in 30+ US states covering 200m+ people. We're growing >25% monthly.
End Close builds automatic reconciliation for payments companies like fintechs, marketplaces, banks and payroll companies. Reconciliation helps companies track every dollar and resolve every exception, ensuring they have no money loss, can report audit ready financials, and stay compliant. Sean (CEO) spent the last 6 years building the reconciliation org at Modern Treasury (S18), processing a trillion dollars in payments across 40 banks with 99.995% automation. Fast growing companies like Modern Treasury are forced to build a solution in-house or buy a legacy solution. End Close provides a modern reconciliation system that works with a company's existing stack and is managed by AI agents. Exception handling is where 99% of the manual work happens today, payment ops teams spend hours gathering context across various data sources to investigate each ticket. End Close provides an AI ops agent that connects to a company's data warehouse, invoicing platform and payment processors to triage and resolve issues without human intervention. Legacy providers only provide reconciliation for month end close applications. End Close continuously reconciles with developer friendly APIs, allowing teams to integrate real time payments data within their products to create product experiences for customers like faster balance top-ups, instant trading etc. New payment rails and agent-to-agent payments are increasing online transaction volumes, making reconciliation a growing challenge for companies. David (CTO and 2nd time YC founder) most recently built these kinds of high-scale ingestion pipelines when starting and leading error tracking at PostHog (W20), the fastest growing product in the company's history.
Engage Bio is developing mRNA immunotherapies to defeat cancer. Our founders have deep experience in immunotherapy development, including four drugs in the clinic, and in building mRNA therapeutics platforms. Our approach is to provide cancer cells with instructions to make and gradually release our drugs within solid tumors. This local therapy allows us to eliminate tumors while sparing healthy distant tissues.
Engines is an AI platform engineer that containerizes codebases, debugs Terraform code, and helps you get complex monorepos setup.
Enhanced Radar is building better, safer air traffic control systems.
Enlightra develops mass-manufacturable fingertip-size multicolor lasers enabling ultrafast data communication and optical computing while providing up to 10x improvement in energy efficiency and cost reduction.
Entangl uses AI to detect and automatically resolve issues in data center engineering and operations, ensuring efficiency and uptime.
Autonomous intake and RCM for specialty clinics. We're helping specialty clinics catapult in to the modern day by automating their patient intake (emails, calls, and faxes) and interactions with payors (insurance companies). We're helping them see patients quicker, keep referrers in the loop, and get paid on time.
Entvin is building AI agents specifically designed to support regulatory teams in the life sciences industry. Our platform leverages AI to streamline workflows, automate complex tasks, and enhance efficiency throughout the regulatory process. By focusing on the unique needs of regulatory teams, we help companies navigate compliance, accelerate approvals, and reduce operational bottlenecks, all while ensuring data security and confidentiality.
Envelope is a banking app with built-in budgeting. It's similar to Mint, Copilot, or Rocket Money, but our app issues you a checking account during onboarding so there's no syncing or flaky bank connections. We are structured to be the primary checking and savings account for our users. We (Josh and Katelyn) are married cofounders who previously worked on Apple Card and the Robinhood iOS app. We started Envelope because we were using clunky tools like the Chase app, spreadsheets, and Mint to run our family finances and realized we could build something better. In the future, you could go set up a Chase account for checking, E-Trade for investing, SoFi for savings, Ally for money market, Greenlight for kid cards, PLUS the Mint/YNAB/Rocket Money to glue it all together + budgeting, or you could just use Envelope. _Envelope is a financial technology company and is not a bank. Banking services provided by Pacific West Bank, Member FDIC. Your funds are FDIC insured up to $250,000 through Pacific West Bank, Member FDIC. The Envelope Visa® Debit Card is issued by Pacific West Bank, N.A. pursuant to a license from Visa U.S.A. Inc. and may be used anywhere Visa cards are accepted._
Epicenter is an ecosystem of open-source, local-first apps that share a memory. We store all your work—notes, transcripts, chat histories—in a single folder of plain text and SQLite. Every tool we build shares this memory: your text editor, personal assistant, etc.. It's open, tweakable, and yours. Grep it, open it in Obsidian, host it wherever you like. The choice is yours. Our vision is to build a personal workspace where you own your data, choose your own AI models, and replace siloed apps with open, interoperable alternatives. All while preserving authenticity and being free and open source. ❤️
Epsilla is an all-in-one platform for building AI agents powered by your private data and knowledge. Easy to use for domain professionals, deeply customizable for AI experts, and fully equipped for enterprise customers with security, scalability, and integration.
Get answers to research questions with citations from the academic literature.
Ergo is AI for sales teams, monitoring customer communication across tools like Zoom, Email, and Slack to keep CRMs such as HubSpot and Salesforce up to date. Ergo’s AI agents execute revenue-generating activities, such as automating mid-funnel follow-ups based on external market signals and past customer interactions. By eliminating manual operational tasks, Ergo helps sales teams maintain active pipelines, prevent deals from stalling, and cut sales cycles in half.
We are developing cancer therapeutics using small molecules that inhibit immune suppression. Our drugs engage the immune system to aggressively fight tumors. Our therapeutic portfolio addresses a range of solid tumors, starting with mesothelioma.
Escape fits right into your modern stack and helps teams secure modern applications— Document all your APIs & front-end applications in minutes and discover vulnerabilities even at a business logic level with our proprietary AI-powered algorithm.
EthosX is a decentralized finance platform creating end-to-end financial derivatives on blockchains. No centralized exchanges, clearinghouses, depositories, clearing banks, CSD participants etc. required. We are starting with cryptocurrency options first, with the intention to move towards other crypto derivatives and traditional finance derivatives eventually. For example, one can buy a bitcoin hedging token directly from EthosX without involving any exchange or counterparty and earn profits when the bitcoin price is falling (similar to a put option). It is perpetual and is completely on-chain, end-to-end. It is held as a token in wallets and can be sold/transferred to anyone at any time. At institutional level, using EthosX’s options infrastructure two hedge funds can trade high-value on-chain options with each other directly without involving any banks or brokers with zero counterparty risk and zero settlement risk. We are also providing derivatives infrastructure to other crypto companies who want to use these products as a part of a larger package to their customers. Global derivatives ecosystem is broken. Derivatives trading in traditional finance has way too many gatekeepers and intermediaries. Crypto was supposed to be free of these issues and a solution to all of this, but it is itself getting more and more centralized with disastrous consequences. We at EthosX intend to pick the best of both worlds and change the way retail and institutional financial derivatives are traded world over.
Eugit Therapeutics targets the issue of non-specific drugs that cause toxicity and clinical trial failures, affecting millions with tissue-specific inflammatory diseases. TAGHOME delivers drugs with precision to diseased tissues using T cell receptors, enhancing safety and improving efficacy. Our initial focus is on the 3.1 million U.S. individuals with Inflammatory Bowel Disease, aiming to initiate clinical trials within two years. Cofounded by George Church (Harvard) and funded by Y Combinator (S22).
We use thousands of AI agents to automate the work of human investors—reading filings, processing news, and finding high-signal events. Our goal is to build a fully autonomous fund that outperforms the best PMs on the planet. Starting with equity long/short.
Every breakthrough AI application, from foundation models to autonomous vehicles, relies on processing massive volumes of images, video, and complex data. But today’s data platforms (like Databricks and Snowflake) are built on top of tools made for spreadsheet-like analytics, not the petabytes of multimodal data that power AI. As a result, teams waste months on brittle infrastructure instead of conducting research and building their core product. Eventual was founded in 2022 to solve this. Our mission is to make querying any kind of data, images, video, audio, text, as intuitive as working with tables, and powerful enough to scale to production workloads. Our open-source engine, Daft, is purpose-built for real-world AI systems: coordinating with external APIs, managing GPU clusters, and handling failures that traditional engines can’t. Daft already powers critical workloads at companies like Amazon, Mobileye, Together AI, and CloudKitchens. We’ve assembled a world-class team from Databricks, AWS, Nvidia, Pinecone, GitHub Copilot, Tesla, and more, quadrupling our size within a year. With backing from Y Combinator, Caffeinated Capital, Array.vc, and top angels from the co-founders of Databricks and Perplexity, we’re looking to double the team now. Join us—Eventual is just getting started. Please note we are looking for someone who is willing and able to come into our San Francisco office in the Mission district 4 days / week.
Outsourced IT is a $350B industry running on 10-20% margins. We're building AI employees to help them solve support tickets faster and increase margins to 70-80%. Yolanda worked as a Senior Support Engineer at Netflix. Her team ran 3x more efficiently than average outsourced IT companies. We're now bringing the automation Netflix has to 150K companies globally.
Setup your entire back-office in one place. - Banking: Bank Accounts, Corporate Cards, Payments, Treasury - Bookkeeping & Tax: Keep you books in order and file income taxes at the end of the year - Payroll and Benefits: US Payroll in 50 states, US Contractors, International Contractors. Health, Vision, Dental, 401k Benefits
🦠🤖 We use our computational models to make next-generation antibiotics that outcompete bacterial evolution and precisely target pathogenic bacteria, without harming good microbes or human cells. ☠️ Current antibiotics stop working because bacteria evolve resistance to them. This makes drug-resistant bacteria a looming global health crisis - already killing more people than malaria and AIDS and it is getting exponentially worse 📈. 🧬 Our approach leverages co-evolutionary protein-protein interaction datasets combined with AI to forecast bacterial mutations and create ‘future-proof’ antibiotics, addressing antibiotic resistance before it develops. This changes the game for how frequently society will need to make new antibiotics and how long our new antibiotics will be able to treat patients 👩⚕️. We are a team of biochemists and evolutionary biologists who met at the University of Oxford.
Evoly makes smart electric & water meters. We save a typical utility over $4M a year. Electric and water meter measure your consumption, A smart meter on the other hand not only measure it, it also send this consumption data and a lot more remotely and wirelessly to the utility. We are a plug and play, easy to install, 5 times cheaper smart metering solution. We are a B2B company and our customer are the Utilities Thanks to our software they get 24/7 view on their grid and a wide range of possibilities : - Remote meter reading - Detecting fraud - Turning electricity on and off remotely - Time of use pricing
Excalipoint Therapeutics is a Shanghai-based biotechnology company developing next-generation T‑cell engager (TCE) therapies for oncology and autoimmune diseases. It advances a pipeline of trispecific and pro‑TCE platforms and funds development through venture financing, strategic partnerships and out‑licensing. Key differentiators include trispecific antibodies, TOPAbody/Pro‑TCE masking and T‑Cell Immune Shield technologies aimed at improving efficacy and safety in solid tumors.
Excellence an after-school maths and science program. We replace/supplement private tutoring and long-term study programs such as Kumon (over 30B TAM). US Parents are our primary customers. Our web and iPad software serves both ambitious and struggling students. As we believe each student is unique, we adapt our high quality courses and exercises to their knowledge and learning style in a very granular way. To facilitate learning, they get detailed text, voice and graphical explanations, can craft study plans, revise and memorize, and received human mentorship if needed. We believe LLMs have made edtech interesting, as technology now allows us to replicate a tutoring learning experience. In addition, we offer a program with daily courses and exercises, detailed feedback on their worksheets and more (super Kumon). Finally we sell the AI tutoring and exercise databases to schools in a B2B and B2B2C model and already work for the most prestigious institutions in France (Ecole polytechnique, college Stanislas...). We're a passionate team of ex-quants, mathematicians and physics champions devoted to improving science education.
Excelsior Sciences is an AI-native biotechnology company that develops a proprietary platform for automated small molecule discovery and manufacturing using its 'blocc chemistry' approach. The company targets pharmaceuticals, materials science, and agtech to replace artisanal chemical synthesis with AI-guided, iterative automation. It generates value through a proprietary therapeutic pipeline and collaborative industry partnerships.
We use AI and high-throughput mouse studies to discover therapeutics that modify neural activity in the brain. The initial focus is on epilepsies associated with autism and Parkinson’s disease with the potential to expand to any neurological disorder underlined by a dysfunction in neural activity. Our R&D is guided by AI models trained on high-density multimodal mouse data generated in-house. We are 3 Oxford-trained neuroscientists supported by an experienced SAB from Harvard, Science Corp (ex-Neuralink), EPFL, Meta, and UCL. In 1.5 months since landing in SF, we went from nothing to (1) opening and operating an animal lab in South SF, (2) obtaining a proof-of-concept in mice, (3) building a multimodal AI model that directs our screening approach and (4) submitting two provisional patents; all while utilizing less than 50% of our YC funding.
Exla aggressively quantizes AI models to minimize memory usage and maximize inference speed. Whether you're deploying LLMs, VLMs, VLAs, or custom models, Exla reduces memory footprint by up to 80% and accelerates inference by 3–20x - all with just a few lines of code. https://cal.com/exla-ai/schedule
Exonic is building a global network of intelligence to cure disease. We are the first drug discovery company open to everyone. Today drug discovery is siloed - secretive, adversarial institutions in glass towers. Biological AI is changing the rules. Every day drug discovery becomes more of a computational problem. Exonic is turning drug discovery into an open, meritocratic tournament. We are advised by world leaders in bio AI, including the former Head of AI at Ginkgo Bioworks, and the first author of Evo (cover of Science). All of the best biological AI models are open source. And on Exonic, you can combine them, prompt them, and share your innovative workflows without writing a single line of code. Using Exonic Studio, we just beat a state-of-the-art benchmark in liver cancer (HepG2) synthetic enhancer design, validated in our wet lab. The platform just went live - you can start right now. We are turning the internet into a drug discovery powerhouse.
Expected Parrot helps companies simulate their customers with AI agents to explore pricing, product, marketing, communications and other scenarios at scale. Our open-source library and no-code web app let you design custom agent personas and conduct interviews and surveys with them using LLMs of your choice to generate results and reports. Everything is cached and reproducible, and you can send the same surveys to human respondents to validate results in the same interface.